Praziquantel

product

Praziquantel

Basic Information:

Praziquantel is an organic compound with the chemical formula C 19 H 24 N 2 O 2 . It is an anthelmintic used in humans and animals. It is specifically used to treat tapeworms and flukes. It is particularly effective against schistosoma japonicum, Chinese liver fluke, and Diphyllobothrium latum.

Chemical formula: C 19 H 24 N 2 O 2

Molecular weight: 312.406

CAS No.: 55268-74-1

EINECS number: 259-559-6


Product Detail

Product Tags

Physicochemical property

Density: 1.22 g/ cm3
Melting point: 136-142°C
Boiling point: 544.1°C
Flash point: 254.6°C
Refractive index: 1.615
Appearance: White or off-white crystalline powder

use

It is mainly used as a broad-spectrum antiparasitic drug for the treatment and prevention of schistosomiasis, cysticercosis, paragonimiasis, echinococcosis, fasciococcus, echinococcosis, and helminth infections.

Characteristics

This product is white or off-white crystalline powder.
This product is easily soluble in chloroform, soluble in ethanol, and insoluble in ether or water.

Melting point

The melting point of this product (General Rule 0612) is 136~141℃.

category

Anthelmintics.

Indications

It is a broad-spectrum drug against trematodes and tapeworms. It is suitable for various schistosomiasis, clonorchiasis, paragonimiasis, fasciolosis, tapeworm disease and cysticercosis.

Pharmacological Action

This product mainly causes spastic paralysis and shedding of schistosomes and tapeworms in the host through 5-HT-like effects. It has good effects on most adult and immature tapeworms. At the same time, it can affect the calcium ion permeability in the muscle cells of the worm body, increase the influx of calcium ions, inhibit the reuptake of sarcoplasmic reticulum calcium pumps, greatly increase the calcium ion content in the muscle cells of the worm body, and cause the worm body to become paralyzed and fall off.

Storage

Keep away from light and store in sealed container.


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